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S. A. G. Visser

GlaxoSmithKline

10

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290

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Model‐Informed Drug Discovery and Development: Current Industry Good Practice and Regulatory Expectations and Future Perspectives

2019
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Common Best Practice in Modeling and Simulation Across Quantitative Disciplines: A Comparison of Independently Emerging Proposals

2018 Statistics in Biopharmaceutical Research
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Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans

2018 Pharmaceutical Research
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5.38 – Mechanism-Based Pharmacokinetic–Pharmacodynamic Modeling for the Prediction of In Vivo Drug Concentration–Effect Relationships – Application in Drug Candidate Selection and Lead Optimization

2007
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Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of the Electroencephalogram Effects of GABAA Receptor Modulators: In Vitro-in Vivo Correlations

2003 Journal of Pharmacology and Experimental Therapeutics
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Mechanism-Based Modeling of the Pharmacodynamic Interaction of Alphaxalone and Midazolam in Rats

2003 Journal of Pharmacology and Experimental Therapeutics
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Neuroactive Steroids Differ in Potency but Not in Intrinsic Efficacy at the GABAA Receptor in Vivo

2002 Journal of Pharmacology and Experimental Therapeutics
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Mechanism-Based Pharmacokinetic-Pharmacodynamic Modeling of Concentration-Dependent Hysteresis and Biphasic Electroencephalogram Effects of Alphaxalone in Rats

2002 Journal of Pharmacology and Experimental Therapeutics
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Dose-Dependent EEG Effects of Zolpidem Provide Evidence for GABAA Receptor Subtype Selectivity in Vivo

2002 Journal of Pharmacology and Experimental Therapeutics
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Citations (27)