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Tim Quach

Monash University

28

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609

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Targeted delivery of mycophenolic acid to the mesenteric lymph node using a triglyceride mimetic prodrug approach enhances gut-specific immunomodulation in mice.

2021 Journal of Controlled Release
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A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

2021 Journal of Biological Chemistry
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Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles.

2021 Pharmaceutical Research
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The impact of conjugation position and linker chemistry on the lymphatic transport of a series of glyceride and phospholipid mimetic prodrugs

2020 Journal of Pharmaceutical Sciences
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Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

2017 Science Translational Medicine
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Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

2017 Nature Communications
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Constitutive Triglyceride Turnover into the Mesenteric Lymph Is Unable to Support Efficient Lymphatic Transport of a Biomimetic Triglyceride Prodrug

2016 Journal of Pharmaceutical Sciences
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Lymphatic transport and lymphocyte targeting of a triglyceride mimetic prodrug is enhanced in a large animal model: studies in greyhound dogs

2016 Molecular Pharmaceutics
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NOX2 oxidase expressed in endosomes exacerbates influenza pathogenicity

2016 European Respiratory Journal
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Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability.

2016 Angewandte Chemie
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Citations (32)