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Roman Hudec

Mayo Clinic

22

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440

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Distinct Missense Mutations of the Parkinson's Disease‐Related Ubiquitin Kinase PINK1 Alter Auto‐ or Substrate‐Phosphorylation

2019 The FASEB Journal
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The PINK1 p.I368N Mutation Affects Protein Stability and Kinase Activity with Its Structural Change

2018 Juntendo Medical Journal
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The PINK1 p.I368N mutation affects protein stability and disrupts kinase activity

2017 Journal of the Neurological Sciences
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Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism

2017 Brain
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Waldenstrom macroglobulinemia cells devoid of BTKC481S or CXCR4WHIM-like mutations acquire resistance to ibrutinib through upregulation of Bcl-2 and AKT resulting in vulnerability towards venetoclax or MK2206 treatment

2017 Blood Cancer Journal
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Reply: Heterozygous PINK1 p.G411S in rapid eye movement sleep behaviour disorder

2017 Brain
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Mitochondrial targeted HSP90 inhibitor Gamitrinib-TPP (G-TPP) induces PINK1/Parkin-dependent mitophagy

2017 Oncotarget
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Non-radioactive in vitro PINK1 Kinase Assays Using Ubiquitin or Parkin as Substrate

2016
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miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1)

2016 Molecular Neurodegeneration
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Additional file 8: of miR-27a and miR-27b regulate autophagic clearance of damaged mitochondria by targeting PTEN-induced putative kinase 1 (PINK1)

2016
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