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Edgor Cole Tolledo
Edgor Cole Tolledo
Centre for Addiction and Mental Health
Haloperidol
Psychology
Catalepsy
Internal medicine
Antipsychotic
5
Papers
35
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A mouse model for investigating human brain CYP2D6
2019
Drug Metabolism and Pharmacokinetics
Edgor Cole Tolledo
Marlaina Stocco
Sharon Miksys
Frank Gonzales
Fariba Baghai Wadji
Bin Zhao
Rachel F. Tyndale
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Propranolol is a mechanism-based inhibitor of CYP2D and CYP2D6 in humanized CYP2D6-transgenic mice: effects on activity and drug response.
2019
British Journal of Pharmacology
Edgor Cole Tolledo
Sharon Miksys
Frank J. Gonzalez
Rachel F. Tyndale
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Citations (3)
Rat brain CYP2D enzymatic metabolism alters acute and chronic haloperidol side-effects by different mechanisms
2017
Progress in Neuro-psychopharmacology & Biological Psychiatry
Sharon Miksys
Fariba Baghai Wadji
Edgor Cole Tolledo
Gary Remington
José N. Nobrega
Rachel F. Tyndale
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Citations (20)
Different dosing regimens of repeated ketamine administration have opposite effects on novelty processing in rats.
2016
Progress in Neuro-psychopharmacology & Biological Psychiatry
Anett Schumacher
Brindan Sivanandan
Edgor Cole Tolledo
Jacob Woldegabriel
Rutsuko Ito
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Citations (12)
Haloperidol-induced catalepsy, a model of acute antipsychotic-induced extrapyramidal side effects, is altered by inhibiting and inducing CYP2D in rat brain
2016
European Neuropsychopharmacology
Sharon Miksys
N Cheng
F. Baghai Wadji
Edgor Cole Tolledo
Rachel F. Tyndale
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