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Richard Harrop

Oxford BioMedica

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Safety and exceptional immunogenicity of novel 5T4 viral vectored vaccination regimes in early stage prostate cancer: a phase I clinical trial

2020 medRxiv
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Cancer stem cell mobilization and therapeutic targeting of the 5T4 oncofetal antigen

2019
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Pre-clinical investigations of CAR T cells directed against the tumour antigen 5T4 (OXB-302) in solid tumor models

2019
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A single centre phase II trial to assess the immunological activity of TroVax® plus pemetrexed/cisplatin in patients with malignant pleural mesothelioma – the SKOPOS trial

2018 OncoImmunology
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VANCE: First-in-human phase I study of a novel ChAdOx1-MVA 5T4 vaccine in low and intermediate risk prostate cancer.

2018 Journal of Clinical Oncology
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MVA-5T4 immunotherapy and low-dose cyclophosphamide for advanced colorectal cancer (TaCTiCC): An open-label, randomized phase I/II trial.

2018 Journal of Clinical Oncology
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MVA-5T4 immunotherapy (TroVax) and low-dose cyclophosphamide for advanced colorectal cancer (TaCTiCC): an open-label, randomized phase 1/2 clinical trial

2017 JAMA Oncology
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Effect of Modified Vaccinia Ankara–5T4 and Low-Dose Cyclophosphamide on Antitumor Immunity in Metastatic Colorectal Cancer: A Randomized Clinical Trial

2017 JAMA Oncology
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5T4 oncofoetal antigen: an attractive target for immune intervention in cancer

2017 Cancer Immunology, Immunotherapy
- Peter L. Stern
- Richard Harrop
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Activity of MVA 5T4 alone or in combination with either interleukin-2 (IL-2) or interferon-α (IFN) in patients (Pts) with metastatic renal cell cancer (MRCC)

2016 Journal of Clinical Oncology
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