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Selvi Durmus

Netherlands Cancer Institute

25

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754

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Targeting PLK1 overcomes T-DM1 resistance via CDK1-dependent phosphorylation and inactivation of Bcl-2/xL in HER2-positive breast cancer

2018 Oncogene
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Systems level analysis of T-DM1 resistance in in vitro and in vivo models of HER-2 overexpressing breast cancer

2016 European Journal of Cancer
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The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice.

2016 Drug Resistance Updates
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Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1) Restrict Oral Availability and Brain Accumulation of the PARP Inhibitor Rucaparib (AG-014699)

2015 Pharmaceutical Research
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Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug–Drug Interactions in Vivo

2015 Molecular Pharmaceutics
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Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide is Dependent on Abcc2, Abcc3, and Oatp1a/1b

2015 Cancer Research
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P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice

2015 Molecular Pharmaceutics
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Brain and Testis Accumulation of Regorafenib is Restricted by Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1)

2015 Pharmaceutical Research
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P-glycoprotein, CYP3A and plasma carboxylesterase determine brain and blood disposition of the mTOR inhibitor everolimus (Afinitor) in mice

2014 Clinical Cancer Research
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Liquid chromatography–tandem mass spectrometric assay for the PARP inhibitor rucaparib in plasma

2014 Journal of Pharmaceutical and Biomedical Analysis
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