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Lijing You

13

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A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy.

2021 Cancer immunology research
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Comparison of the superagonist complex, ALT-803, to IL15 as cancer immunotherapeutics in animal models

2016 Cancer immunology research
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Novel antitumor mechanism-of-action of an IL-2 fusion protein mediated by tumor associated macrophage repolarization and innate-like CD8+ memory T cells

2014 Journal for ImmunoTherapy of Cancer
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Intravesical ALT-803 and BCG Treatment Reduces Tumor Burden in a Carcinogen Induced Bladder Cancer Rat Model; a Role for Cytokine Production and NK Cell Expansion

2014 PLOS ONE
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Interleukin-15:Interleukin-15 receptor α scaffold for creation of multivalent targeted immune molecules

2011 Protein Engineering Design & Selection
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Targeting activity of a TCR/IL-2 fusion protein against established tumors

2008 Cancer Immunology, Immunotherapy
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Peptide-loading enhancement for antigen presenting cells

2007 Journal of Immunology
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Recognition of Melanoma-Associated Antigens gp100 or Mart1/Melan-A in the Context of HLA-A2 by Soluble Single Chain T-Cell Receptor Multimers

2007 Journal of Immunology
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Cell-based Mechanism of Action of a TCR/IL-2 Fusion Protein against Established Tumors

2007 Journal of Immunology
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