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A. Robert MacLeod

Isis Pharmaceuticals

88

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Abstract ND11: The discovery and characterization of ION-537: A next generation antisense oligonucleotide inhibitor of YAP1 in preclinical cancer models

2021 Cancer Research
- A. Robert MacLeod
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Correction to: LncRNA PVT1 up-regulation is a poor prognosticator and serves as a therapeutic target in esophageal adenocarcinoma.

2021 Molecular Cancer
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Plasma Kallikrein Contributes to Intracerebral Hemorrhage and Hypertension in Stroke-Prone Spontaneously Hypertensive Rats

2021 Translational Stroke Research
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Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption

2021 Cell Stem Cell
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Sensitive intranuclear flow cytometric quantification of IRF4 protein in multiple myeloma and normal human hematopoietic cells.

2021
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Antisense oligonucleotide activity in tumour cells is influenced by intracellular LBPA distribution and extracellular vesicle recycling.

2021
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Abstract B08: Therapeutic inhibition of YAP1 expression by next-generation antisense oligonucleotides leads to antitumor activity in head and neck squamous cell carcinoma with YAP1 activation

2020 Molecular Cancer Research
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Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma.

2020 Retrovirology
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Selective Antisense Oligonucleotide Inhibition of Human IRF4 Prevents Malignant Myeloma Regeneration Via Cell Cycle Disruption

2020 Social Science Research Network
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Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines

2019 Nucleic Acids Research
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