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Yulius Y. Setiady

ImmunoGen, Inc.

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A CD123-targeting antibody-drug conjugate, IMGN632, designed to eradicate AML while sparing normal bone marrow cells

2018 Blood Advances
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Abstract 753: Development of an in vivo model system to assess the interplay between the various drivers of antibody-drug conjugate (ADC) activity

2018 Cancer Research
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Effects of Drug–Antibody Ratio on Pharmacokinetics, Biodistribution, Efficacy, and Tolerability of Antibody–Maytansinoid Conjugates

2017 Bioconjugate Chemistry
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Abstract 2186: Peptide-cleavable maytansinoid (ADCs) induce high bystander killing leading to improved anti-tumor activityin vivo

2017 Cancer Research
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Abstract 71: Bystander activity andin vivoefficacy of a folate receptor α (FRα)-targeting antibody-drug conjugate with a novel peptide linker

2017 Cancer Research
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A new, triglycyl peptide linker for antibody-drug conjugates (ADCs) with improved targeted killing of cancer cells

2016 Molecular Cancer Therapeutics
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Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing.

2015 Bioconjugate Chemistry
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Evaluation of Targets for Maytansinoid ADC Therapy Using a Novel Radiochemical Assay.

2015 Pharmaceutical Research
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Abstract A52: Extracellular matrix regulation of ErbB3 in a subset of wild-type BRAF/NRAS melanoma

2015 Molecular Cancer Therapeutics
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Abstract B130: Correlation of in vitro cytotoxicity and catabolism of antibody-drug conjugates (ADCs) in target cancer cells

2015 Molecular Cancer Therapeutics
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