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Shane Grealish

Lund University

24

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2065

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hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Disease

2019 Cell Reports
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IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells

2017 Stem cell reports
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Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli.

2017 Brain
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Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

2017 Cell Stem Cell
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Plug and Play Brain: Understanding Integration of Transplanted Neurons for Brain Repair.

2016 Cell Stem Cell
- Shane Grealish
- Malin Parmar
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Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain

2015 Scientific Reports
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Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons.

2015 Stem cell reports
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Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

2014 Cell Stem Cell
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Generation of induced neurons via direct conversion in vivo

2013 Proceedings of the National Academy of Sciences of the United States of America
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Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism

2013 Proceedings of the National Academy of Sciences of the United States of America
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Citations (18)