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John Lyons
John Lyons
Onyx Pharmaceuticals
Kinase
Signal transduction
Biochemistry
Raf kinase
Enzyme
3
Papers
117
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Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach.
2001
Bioorganic & Medicinal Chemistry Letters
Roger A. Smith
James Barbosa
Cheri Lynn Blum
Mark Bobko
Yolanda V Caringal
Robert Dally
Jeffrey S. Johnson
Michael E. Katz
Nancy Kennure
Jill Kingery-Wood
Wendy Lee
Timothy B. Lowinger
John Lyons
Vivienne Marsh
Daniel H Rogers
Stephen Swartz
Tracy Walling
Hanno Wild
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Citations (78)
C3 Toxin Activates the Stress Signaling Pathways, JNK and p38, but Antagonizes the Activation of AP-1 in Rat-1 Cells
1999
Journal of Biological Chemistry
Jerlyn Beltman
James R. Erickson
George A. Martin
John Lyons
Simon J. Cook
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Citations (39)
Inhibidores de raf-quinasa.
1998
Jill E. Wood
Hanno Wild
Daniel H Rogers
John Lyons
Michael E Katz
Yolanda V Caringal
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1