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Stephen E. Kearsey

University of Oxford

79

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4010

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Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication

2021 bioRxiv
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Set2 Methyltransferase Facilitates DNA Replication and Promotes Genotoxic Stress Responses through MBF-Dependent Transcription

2017 Cell Reports
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A panoply of errors: polymerase proofreading domain mutations in cancer.

2016 Nature Reviews Cancer
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Real-Time Imaging of DNA Damage in Yeast Cells Using Ultra-Short Near-Infrared Pulsed Laser Irradiation

2014 PLOS ONE
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Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis

2013 Molecular Biology of the Cell
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Ribonucleotide Reductase Activity Is Coupled to DNA Synthesis via Proliferating Cell Nuclear Antigen

2012 Current Biology
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Direct Role for Proliferating Cell Nuclear Antigen in Substrate Recognition by the E3 Ubiquitin Ligase CRL4Cdt2

2012 Journal of Biological Chemistry
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Monitoring DNA replication in fission yeast by incorporation of 5-ethynyl-2′-deoxyuridine

2011 Nucleic Acids Research
- Hui Hua
- Stephen E. Kearsey
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Cdt1 proteolysis is promoted by dual PIP degrons and is modulated by PCNA ubiquitylation

2011 Nucleic Acids Research
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ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast

2010
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Citations (8)