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Kirsten M. Edwards
Kirsten M. Edwards
Ludwig Institute for Cancer Research
Cytotoxic T cell
Biology
Granzyme B
Granzyme
Perforin
3
Papers
208
Citations
0.01
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Discordant Regulation of Granzyme H and Granzyme B Expression in Human Lymphocytes
2004
Journal of Biological Chemistry
Karin A Sedelies
Thomas J. Sayers
Kirsten M. Edwards
Weisan Chen
Daniel G. Pellicci
Dale I. Godfrey
Joseph A. Trapani
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Citations (76)
The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes.
1999
Journal of Biological Chemistry
Kirsten M. Edwards
Chih-Min Kam
James C. Powers
Joseph A. Trapani
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Citations (94)
Anti-viral strategies of cytotoxic T lymphocytes are manifested through a variety of granule-bound pathways of apoptosis induction.
1999
Immunology and Cell Biology
Kirsten M. Edwards
Joanne E. Davis
Kylie A. Browne
Vivien R. Sutton
Joseph A. Trapani
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Citations (38)
1