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Seungheon Lee
Seungheon Lee
University of Houston
Chemistry
Docking (molecular)
Enzyme
Inosine-5′-monophosphate dehydrogenase
NAD binding
3
Papers
1
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0
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2024
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Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling
2021
European Journal of Medicinal Chemistry
Sameer Nikhar
Ioannis Siokas
Lisa Schlicher
Seungheon Lee
Mads Gyrd-Hansen
Alexei Degterev
Gregory D. Cuny
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Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor.
2021
Cell Death and Disease
Tom Delanghe
Jon Huyghe
Seungheon Lee
Dario Priem
Samya Van Coillie
Barbara Gilbert
Sze Men Choi
Peter Vandenabeele
Alexei Degterev
Gregory D. Cuny
Yves Dondelinger
Mathieu J.M. Bertrand
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Mycophenolic anilides as broad specificity inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors.
2020
Bioorganic & Medicinal Chemistry Letters
Seungheon Lee
Angela Ku
Mohana Rao Vippila
Yong Wang
Minjia Zhang
Xingyou Wang
Lizbeth Hedstrom
Gregory D. Cuny
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