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Deepak Thakker

Novartis

13

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456

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Widespread brain distribution and activity following i.c.v. infusion of anti‐β‐secretase (BACE1) in nonhuman primates

2017 British Journal of Pharmacology
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Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse.

2013 Neuropharmacology
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Efficacy and safety of systemic versus intracerebroventricular delivery of a β-secretase (BACE1) small molecule inhibitor in a mouse model of Alzheimer's disease

2011 Alzheimers & Dementia
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Anticorps anti-amyloïde bêta conjugués à des molécules contenant de l'acide sialique

2010
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Intracerebroventricular amyloid-β antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice

2009 Proceedings of the National Academy of Sciences of the United States of America
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Procédés et dispositif permettant de neutraliser des agents solubles toxiques dans le cerveau

2008
- Lisa L. Shafer
- Deepak Thakker
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Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders.

2006 Journal of Receptors and Signal Transduction
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P.4.09 Behavioural and neurochemical consequencesof sIRNA-induced knockdown of serotonin and dopamine transporters in the adult mouse brain: Implications for validation of novel antidepressant targets

2005 European Neuropsychopharmacology
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Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

2004 Proceedings of the National Academy of Sciences of the United States of America
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Citations (202)