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Lorin Roskos

AstraZeneca

16

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289

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Chronic pharmacological antagonism of murine GM-CSF-R-alpha does not replicate the Pulmonary Alveolar Proteinosis phenotype but does alter lung surfactant turnover

2021 Clinical Science
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A Novel Pharmacodynamic Biomarker and Mechanistic Modeling Facilitate the Development of Tovetumab, a Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor Alpha, for Cancer Therapy.

2021 Aaps Journal
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Pharmacokinetic and Pharmacodynamic Modeling of Tezepelumab to Guide Phase 3 Dose Selection for Patients With Severe Asthma.

2021 The Journal of Clinical Pharmacology
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Exposure-Response Analysis for Selection of Optimal Dosage Regimen of Anifrolumab in Patients With Systemic Lupus Erythematosus.

2021 Rheumatology
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Overall survival modeling and association with serum biomarkers in durvalumab-treated patients with head and neck cancer.

2020 Journal of Clinical Oncology
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Molecular Mechanism of HER2 Rapid Internalization and Redirected Trafficking Induced by Anti-HER2 Biparatopic Antibody.

2020 Antibodies
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A new method for identification of outliers in immunogenicity assay cut point data.

2020 Journal of Immunological Methods
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A novel approach to assess domain specificity of anti-drug antibodies to moxetumomab pasudotox, an immunotoxin with two functional domains

2019 Journal of Immunological Methods
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Detecting bliss synergy in in vivo combination studies with a tumor kinetic model

2019 Pharmaceutical Statistics
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1557. Population Pharmacokinetics of Suvratoxumab (MEDI4893), an Extended Half-life Staphylococcus aureus Alpha Toxin-Neutralizing Human Monoclonal Antibody, in Healthy Adults and Patients on Mechanical Ventilation in Intensive Care Units

2019 Open Forum Infectious Diseases
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