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Cheng-Liang Kuo

National Health Research Institutes

5

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Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis

2020 Cancer Letters
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Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity

2018 Cell Death and Disease
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Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer.

2017 Scientific Reports
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Mitochondrial Lon regulates apoptosis through the association with Hsp60–mtHsp70 complex

2015 Cell Death and Disease
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