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Bill H. Diplas

Duke University

34

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2408

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The KDM5 Family of Histone Lysine Demethylases Are Targets of R-2-Hydroxyglutarate in IDH Mutant Tumors

2021 Blood
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Abstract 5821: The role of SMARCAL1 loss-of-function mutations in glioblastoma telomere maintenance

2020 Cancer Research
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The integrated genomic and epigenomic landscape of brainstem glioma.

2020 Nature Communications
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Targeting Mutant PPM1D Sensitizes Diffuse Intrinsic Pontine Glioma Cells to the PARP Inhibitor Olaparib.

2020 Molecular Cancer Research
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Genome-wide CRISPR-Cas9 screen reveals selective vulnerability of ATRX-mutant cancers to WEE1 inhibition

2019 Cancer Research
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Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy

2019 Proceedings of the National Academy of Sciences of the United States of America
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CRISPR editing of mutant IDH1 R132H induces a CpG methylation-low state in patient-derived glioma models of G-CIMP

2019 Molecular Cancer Research
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Adaptive evolution of the GDH2 allosteric domain promotes gliomagenesis by resolving IDH1R132H induced metabolic liabilities

2018 Cancer Research
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GENE-42. THE GENOMIC LANDSCAPE OF TRIPLE-NEGATIVE GLIOBLASTOMA

2018 Neuro-oncology
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Mutant allele quantification reveals a genetic basis for TP53 mutation-driven castration resistance in prostate cancer cells

2018 Scientific Reports
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