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Karen K. Takane

University of Pittsburgh

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Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells

2015 Diabetes
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Cytoplasmic-Nuclear Trafficking of G1/S Cell Cycle Molecules and Adult Human β-Cell Replication: A Revised Model of Human β-Cell G1/S Control

2013 Diabetes
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c-myc and skp2 Coordinate p27 Degradation, Vascular Smooth Muscle Proliferation, and Neointima Formation Induced by the Parathyroid Hormone-Related Protein

2012 Endocrinology
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ChREBP Mediates Glucose-Stimulated Pancreatic β-Cell Proliferation

2012 Diabetes
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Activation of Protein Kinase C-ζ in Pancreatic β-Cells In Vivo Improves Glucose Tolerance and Induces β-Cell Expansion via mTOR Activation

2011 Diabetes
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cMyc Is a Principal Upstream Driver of β-Cell Proliferation in Rat Insulinoma Cell Lines and Is an Effective Mediator of Human β-Cell Replication

2011 Molecular Endocrinology
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Parathyroid hormone-related protein enhances human β-cell proliferation and function with associated induction of cyclin-dependent-kinase 2 and cyclin E expression

2010 Diabetes
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Abstract 20709: The Parathyroid Hormone-related Peptide (PTHrP) Induces Arterial Vascular Smooth Muscle Cell Proliferation and Neointima Formation via a Skp2 and C-myc Dependent Pathway.

2010 Circulation
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Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

2010 Diabetes
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O43 La compartimentalisation des sub-domaines de la membrane plasmique contribue à des mécanismes d’action des céramides différents sur la voie de signalisation de l’insuline

2010 Diabetes & Metabolism
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