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Christian Sevel
Christian Sevel
Vanderbilt University Medical Center
Biochemistry
Chemistry
Stereochemistry
Structure–activity relationship
Organic chemistry
5
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55
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Drug change: ‘a hassle like no other’. An in-depth investigation using the Danish patient safety database and focus group interviews with Danish hospital personnel:
2019
Therapeutic advances in drug safety
Joo Hanne Poulsen
Rikke Mie Rishøj
Hanne Fischer
Trine Kart
Lotte Stig Nørgaard
Christian Sevel
Peter Dieckmann
Marianne Hald Clemmensen
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Citations (4)
Further exploration of M1 allosteric agonists: Subtle structural changes abolish M1 allosteric agonism and result in pan-mAChR orthosteric antagonism
2013
Bioorganic & Medicinal Chemistry Letters
Douglas J. Sheffler
Christian Sevel
Uyen M. Le
Kimberly M. Lovell
James C. Tarr
Sheridan J. S. Carrington
Hyekyung P. Cho
Gregory J. Digby
Colleen M. Niswender
P. Jeffrey Conn
Corey R. Hopkins
Michael R. Wood
Craig W. Lindsley
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Citations (8)
Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012.
2012
Bioorganic & Medicinal Chemistry Letters
Bruce J. Melancon
Thomas J. Utley
Christian Sevel
Margrith E. Mattmann
Yiu-Yin Cheung
Thomas M. Bridges
Ryan D. Morrison
Douglas J. Sheffler
Colleen M. Niswender
J. Scott Daniels
P. Jeffrey Conn
Craig W. Lindsley
Michael R. Wood
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Citations (12)
Synthesis and biological characterization of a series of novel diaryl amide M1 antagonists
2012
Bioorganic & Medicinal Chemistry Letters
Michael S. Poslusney
Christian Sevel
Thomas J. Utley
Thomas M. Bridges
Ryan D. Morrison
Nathan R. Kett
Douglas J. Sheffler
Colleen M. Niswender
Daniels Js
P.J. Conn
Craig W. Lindsley
Michael R. Wood
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Chemical modification of the M(1) agonist VU0364572 reveals molecular switches in pharmacology and a bitopic binding mode.
2012
ACS Chemical Neuroscience
Gregory J. Digby
Thomas J. Utley
Atin Lamsal
Christian Sevel
Douglas J. Sheffler
Evan P. Lebois
Thomas M. Bridges
Michael R. Wood
Colleen M. Niswender
Craig W. Lindsley
P. Jeffrey Conn
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Citations (26)
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