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Marijke Somers

Johnson & Johnson Pharmaceutical Research and Development

7

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Discovery of 8-Trifluoromethyl-3-cyclopropylmethyl-7-[(4-(2,4-difluorophenyl)-1-piperazinyl)methyl]-1,2,4-triazolo[4,3-a]pyridine (JNJ-46356479), a Selective and Orally Bioavailable mGlu2 Receptor Positive Allosteric Modulator (PAM)

2016 Journal of Medicinal Chemistry
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Discovery of a potent, selective, and orally active phosphodiesterase 10A inhibitor for the potential treatment of schizophrenia.

2014 Journal of Medicinal Chemistry
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Inhibitor-based validation of a homology model of the active-site of tripeptidyl peptidase II

2005 Journal of Molecular Graphics & Modelling
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JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist

2004 Neuropharmacology
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Citations (122)