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Ikuko Nagasawa
Ikuko Nagasawa
Japanese Foundation for Cancer Research
Kinase
Melanoma
Cancer research
Integrated stress response
ATF4
4
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16
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GZD824 inhibits GCN2 and sensitizes cancer cells to amino acid starvation stress.
2020
Molecular Pharmacology
Yu Kato
Kazuhiro Kunimasa
Mizuki Takahashi
Ayaka Harada
Ikuko Nagasawa
Masanori Osawa
Yoshikazu Sugimoto
Akihiro Tomida
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Citations (4)
Disrupting ATF4 expression mechanisms provides an effective strategy for BRAF-targeted melanoma therapy
2020
iScience
Ikuko Nagasawa
Masaru Koido
Yuri Tani
Satomi Tsukahara
Kazuhiro Kunimasa
Akihiro Tomida
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BRAF-mutated cells activate GCN2-mediated integrated stress response as a cytoprotective mechanism in response to vemurafenib
2017
Biochemical and Biophysical Research Communications
Ikuko Nagasawa
Kazuhiro Kunimasa
Satomi Tsukahara
Akihiro Tomida
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Citations (9)
Abstract 4658: Activation mechanisms of Integrated Stress Response by inhibition of oncogenic BRAF in melanoma cell lines
2016
Cancer Research
Ikuko Nagasawa
Satomi Tsukahara
Kazuhiro Kunimasa
Akihiro Tomida
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