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Miroslav Varecha

Masaryk University

52

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476

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Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling.

2021 Journal of Bone and Mineral Research
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Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling

2020 Embo Molecular Medicine
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Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome

2018 Cellular Signalling
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Regulation of ciliary function by fibroblast growth factor signaling identifies FGFR3-related disorders achondroplasia and thanatophoric dysplasia as ciliopathies

2018 Human Molecular Genetics
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TEC controls pluripotency and early cell fate decisions of human pluripotent stem cells via regulation of FGF2 secretion

2017 Stem Cells
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Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480

2017 Oncotarget
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Differences in anterior-posterior sensitivity of early limb bud cell to FGF/WNT treatment

2017
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Statins do not inhibit the FGFR signaling in chondrocytes

2017 Osteoarthritis and Cartilage
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ARQ 087 inhibits FGFR signaling and rescues aberrant cell proliferation and differentiation in experimental models of craniosynostoses and chondrodysplasias caused by activating mutations in FGFR1, FGFR2 and FGFR3

2017 Bone
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One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

2017 eLife
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