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Mayu Nishino

Juntendo University

5

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4-(3-Chloro-4-methoxybenzyl)aminophthalazines: synthesis and inhibitory activity toward phosphodiesterase 5.

2000 Journal of Medicinal Chemistry
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E-4010, a selective phosphodiesterase 5 inhibitor, attenuates hypoxic pulmonary hypertension in rats.

1999 American Journal of Physiology-lung Cellular and Molecular Physiology
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CORONARY ARTERY DIAMETER INCREASE INDUCED BY A PHOSPHODIESTERASE 5 INHIBITOR, E4021, IN CONSCIOUS PIGS

1998 Japanese Journal of Pharmacology
- Hideyuki Adachi
- Mayu Nishino
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[E 4021, a cGMP phosphodiesterase inhibitor, is a selective pulmonary vasodilator in chronically hypoxic pulmonary hypertensive rats].

1998 The journal of the Japanese Respiratory Society
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Hypotensive effects of a novel phosphodiesterase V inhibitor, E4021, in rats

1995 Japanese Journal of Pharmacology
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