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Mani Larijani

Memorial University of Newfoundland

48

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P-120: Improving the risk stratification of multiple myeloma with a nucleotide editor/inflammation-based scoring system

2021 Clinical Lymphoma, Myeloma & Leukemia
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Structure-Based Design of First-Generation Small Molecule Inhibitors Targeting the Catalytic Pockets of AID, APOBEC3A, and APOBEC3B.

2021
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Identification of Previously Unrecognized Multiple Myeloma Risk Subgroups with a Novel Biological Disease Stratifier

2021 Blood
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Activation-induced cytidine deaminase can target multiple topologies of double-stranded DNA in a transcription-independent manner.

2020 The FASEB Journal
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Structural plasticity of substrate selection by activation-induced cytidine deaminase as a regulator of its genome-wide mutagenic activity

2020 FEBS Letters
- Justin J. King
- Mani Larijani
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APOBEC3G Regulation of the Evolutionary Race Between Adaptive Immunity and Viral Immune Escape Is Deeply Imprinted in the HIV Genome

2019 Frontiers in Immunology
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Pichia pastoris as a host for production and isolation of mutagenic AID/APOBEC enzymes involved in cancer and immunity

2019 New Biotechnology
- Faezeh Borzooee
- Mani Larijani
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Enhancement of Cancer-Specific Protoporphyrin IX Fluorescence by Targeting Oncogenic Ras/MEK Pathway

2018 Theranostics
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Expansions, diversification, and interindividual copy number variations of AID/APOBEC family cytidine deaminase genes in lampreys

2018 Proceedings of the National Academy of Sciences of the United States of America
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DNA/RNA hybrid substrates modulate the catalytic activity of purified AID

2018 Molecular Immunology
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