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Karen A. Evans

GlaxoSmithKline

21

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451

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LB985 GSK2967901A, a novel small molecule SIRT1 activator for the topical treatment of psoriasis

2017 Journal of Investigative Dermatology
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Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity

2015 Molecular Pharmacology
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Synthesis of 2,5-disubstituted-3-cyanoindoles

2012 Tetrahedron Letters
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Synthesis of 2,5-disubstituted-3-cyanoindoles

2012 Tetrahedron Letters
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Novel Synthesis of 5-Amino-3-bromo-1-(tert-butyl)-1H-pyrazole-4-carbonitrile: A Versatile Intermediate for the Preparation of 5-Amino-3-aryl-1-(tert-butyl)-1H-pyrazole-4-carboxamides

2012 Organic Letters
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Phenoxyacetic acid PPARd partial agonists for the treatment of type 2 diabetes: synthesis, optimization, and in vivo efficacy

2011 Bioorganic & Medicinal Chemistry Letters
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Phenoxyacetic acids as PPARδ partial agonists: Synthesis, optimization, and in vivo efficacy

2011 Bioorganic & Medicinal Chemistry Letters
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Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists.

2010 ACS Medicinal Chemistry Letters
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3-Urea-1-(phenylmethyl)-pyridones as novel, potent, and selective EP3 receptor antagonists.

2010 Bioorganic & Medicinal Chemistry Letters
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Synthesis and structure–activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists

2010 Bioorganic & Medicinal Chemistry Letters
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Citations (38)