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Julian Jack
Julian Jack
Wolfson Centre for Age-Related Diseases
Agonist
Biochemistry
Retinoic acid receptor
Nerve injury
Chemistry
5
Papers
78
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RARβ agonist drug (C286) demonstrates efficacy in a pre-clinical neuropathic pain model restoring multiple pathways via DNA repair mechanisms
2019
iScience
Maria B. Goncalves
Julien Moehlin
Earl Clarke
John Grist
Carl Hobbs
Antony Carr
Julian Jack
Marco Antonio Mendoza-Parra
Jonathan Corcoran
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Citations (2)
Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells
2019
The Journal of Neuroscience
Maria B. Goncalves
Yue Wu
Earl Clarke
John Grist
Carl Hobbs
Diogo Trigo
Julian Jack
Jonathan Corcoran
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Citations (16)
Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury
2019
Bioorganic & Medicinal Chemistry Letters
Maria B. Goncalves
Earl Clarke
Christopher I. Jarvis
S. Barret Kalindjian
Thomas Pitcher
John Grist
Carl Hobbs
Thomas P. Carlstedt
Julian Jack
Jane Theresa Brown
Mark Mills
Peter Mumford
Alan D. Borthwick
Jonathan Corcoran
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Citations (3)
Corrigendum to “Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury” [Bioorg. Med. Chem. Lett. 29(8) (2019) 995–1000]
2019
Bioorganic & Medicinal Chemistry Letters
Maria B. Goncalves
Earl Clarke
Christopher I. Jarvis
S. Barret Kalindjian
Thomas Pitcher
John Grist
Carl Hobbs
Thomas Carlstedt
Julian Jack
Jane T. Brown
Mark Mills
Peter Mumford
Alan D. Borthwick
Jonathan Corcoran
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