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Michael A. Stashko

University of North Carolina at Chapel Hill

55

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Development of [18F]MIPS15692, a radiotracer with in vitro proof-of-concept for the imaging of MER tyrosine kinase (MERTK) in neuroinflammatory disease.

2021 European Journal of Medicinal Chemistry
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AD Informer Set: Chemical tools to facilitate Alzheimer’s disease drug discovery

2021 bioRxiv
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MerTK activity is not necessary for the proliferation of glioblastoma stem cells.

2021 Biochemical Pharmacology
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Use of Protein Kinase–Focused Compound Libraries for the Discovery of New Inositol Phosphate Kinase Inhibitors

2018
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Highly Selective MERTK Inhibitors Achieved by a Single Methyl Group

2018 Journal of Medicinal Chemistry
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Discovery of Macrocyclic Pyrimidines as MerTK‐Specific Inhibitors

2017 ChemMedChem
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Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2541

2017
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Retraction: A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors (PLoS ONE (2016) 11, 10 (e0164378) DOI: 10.1371/journal.pone.0164378)

2017 PLOS ONE
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The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia

2016 JCI insight
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A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors

2016 PLOS ONE
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