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Cedric Darini
Cedric Darini
Jewish General Hospital
Biology
Carcinogenesis
Cancer research
Molecular biology
KRAS
4
Papers
41
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The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer.
2021
Nature Communications
Nour Ghaddar
Shuo Wang
Bethany Woodvine
Jothilatha Krishnamoorthy
Vincent van Hoef
Cedric Darini
Urszula Kazimierczak
Nicolas Ah-son
H. Popper
Myriam Johnson
Leah Officer
Ana Teodosio
Massimo Broggini
Koren K. Mann
Maria Hatzoglou
Ivan Topisirovic
Ola Larsson
John Le Quesne
Antonis E. Koromilas
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Citations (1)
An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy
2019
Nature Communications
Cedric Darini
Nour Ghaddar
Catherine Chabot
Gloria Assaker
Siham Sabri
Shuo Wang
Jothilatha Krishnamoorthy
Marguerite Buchanan
Adriana Aguilar-Mahecha
Bassam Abdulkarim
Jean Deschenes
Jose Torres
Josie Ursini-Siegel
Mark Basik
Antonis E. Koromilas
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Citations (21)
Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells
2018
Cell Death and Disease
Jothilatha Krishnamoorthy
Clara Tenkerian
Jyotsana Gupta
Nour Ghaddar
Shuo Wang
Cedric Darini
Kirk A Staschke
Abhishek Ghosh
Valentina Gandin
Ivan Topisirovic
Arnold S. Kristof
Maria Hatzoglou
George Simos
Antonis E. Koromilas
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Citations (6)
STAT1 Promotes KRAS Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A
2016
Molecular Cancer Therapeutics
Shuo Wang
Cedric Darini
Laurent Désaubry
Antonis E. Koromilas
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Citations (13)
1