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Pelosi Elvira

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Isocitrate Dehydrogenase Mutations in Human Cancers: Physiopathologic Mechanisms and Therapeutic Targeting

2016
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In hypoxia, HIF-1α is a direct transcriptional repressor of TM9SF4 in leukemic cells.

2015 PLOS ONE
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Stabilization of HIF-1α by DMOG treatment of leukemic cells grown in normoxia, mimics hypoxia and then decreases TM9SF4 expression.

2015 PLOS ONE
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TM9SF4 decreases during vitamin D3-induced Mo differentiation of U937 cells, but increases during ATRA-induced G differentiation of HL-60 cells.

2015 PLOS ONE
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