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Xuefeng Wu

University of California, San Diego

27

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2104

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Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas

2017 Cancer Cell
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Citations (69)
PI3Kγ is a molecular switch that controls immune suppression

2016 Nature
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TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis

2014 Journal of Clinical Investigation
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Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.

2014 Proceedings of the National Academy of Sciences of the United States of America
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STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13

2014 Nature Communications
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Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice

2013 Journal of Clinical Investigation
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Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells

2012 Nature Immunology
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Crystal structure of inhibitor of [kgr]B kinase [bgr]

2011 Nature
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Crystal structure of inhibitor of κB kinase β

2011 Nature
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Crystal structure of inhibitor of κB kinase β (IKKβ)

2011 Nature
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Citations (5)