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Qi Ziping
Qi Ziping
Biochemistry
Chemistry
Cancer research
Proto-oncogene tyrosine-protein kinase Src
CHMFL-ABL-053
4
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独特なヒンジ結合を示す新しい,非常に強力なII型ABL/KIT二重キナーゼ阻害剤としての4‐メチル‐N‐(4‐((4‐メチルピペラジン‐1‐イル)メチル)‐3‐(トリフルオロメチル)フェニル)‐3‐((1‐ニコチノイルピペリジン‐4‐イル)オキシ)ベンズアミド(CHMFL‐ABL/KIT‐155)の発見
2017
Journal of Medicinal Chemistry
Wang Qiang
Liu Feiyang
Wang Beilei
Zou Fengming
Qi Ziping
Chen Cheng
Yu Kailin
Hu Chen
Qi Shuang
Wang Wenchao
Hu Zhenquan
Liu Juan
Wang Wei
Wang Li
Liang Qianmao
Zhang Shanchun
Ren Tao
Liu QingSong
Liu Jing
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慢性骨髄性白血病に対する強力で選択的な,かつ経口投与可能なBCR‐ABL/SRC/p38キナーゼ阻害剤としての2‐((3‐アミノ‐4‐メチルフェニル)アミノ)‐N‐(2‐メチル‐5‐(3‐(トリフルオロメチル)ベンズアミド)フェニル)‐4‐(メチルアミノ)ピリミジン‐5‐カルボキサミド(CHMFL‐ABL‐053)の発見
2016
Journal of Medicinal Chemistry
Liang Xiaofei
Liu Xiaochuan
Wang Beilei
Zou Fengming
Wang Aoli
Qi Shuang
Chen Cheng
Zhao Zheng
Wang Wenchao
Qi Ziping
Li Fengchao
Hu Zhenquan
Wang Li
Zhang Shanchun
Liu QingSong
Liu Jing
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消化管間質腫瘍(GIST)のための選択的で強力な経口投与可能なII型c‐KITキナーゼ阻害剤としてのN‐(3‐((1‐イソニコチノイルピペリジン‐4‐イル)オキシ)‐4‐メチルフェニル)‐3‐(トリフロロメチル)ベンズアミド(CHMFL‐KIT‐110)の発見
2016
Journal of Medicinal Chemistry
Wang Qiang
Liu Feiyang
Wang Beilei
Zou Fengming
Chen Cheng
Liu Xiaochuan
Wang Aoli
Qi Shuang
Wang Wenchao
Qi Ziping
Zhao Zheng
Hu Zhenquan
Wang Wei
Wang Li
Zhang Shanchun
Wang Yuexiang
Liu Jing
Liu QingSong
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Novel kinase inhibitor against wild-type and mutant egfr
2016
Qingsong Liu
Jing Liu
Xixiang Li
Aoli Wang
Hong Wu
Yu Kailin
Chen Hu
Wenchao Wang
Cheng Chen
Fengming Zou
Qi Ziping
Li Wang
Beilei Wang
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