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Shripad S. Bhagwat

Ambit Biosciences

21

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704

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Novel series of pyrrolotriazine analogs as highly potent pan-Aurora kinase inhibitors

2011 Bioorganic & Medicinal Chemistry Letters
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4-Quinazolinyloxy-diaryl ureas as novel BRAFV600E inhibitors.

2011 Bioorganic & Medicinal Chemistry Letters
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Abstract 3619: Inhibition of FLT3 autophosphorylation and downstream signaling both in vitro and in vivo by AC220, a second generation potent and selective FLT3 inhibitor

2010 Cancer Research
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AC220, a Potent and Specific FLT3 Inhibitor, Enhances the Cytotoxic Effects of Chemotherapeutic Agents in Cell Culture and in Mouse Tumor Xenografts.

2009 Blood
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Arylcarboxyamino-substituted diaryl ureas as potent and selective FLT3 inhibitors

2009 Bioorganic & Medicinal Chemistry Letters
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Abstract #2335: AC220, a uniquely potent and selective FLT3 inhibitor, provides sustained protection in a FLT3 ITD driven model of acute myeloid leukemia

2009 Cancer Research
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Kinase inhibitors for the treatment of inflammatory and autoimmune disorders

2009 Purinergic Signalling
- Shripad S. Bhagwat
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Abstract #5651: Intermittent pan-HER inhibition with AC480 in combination with paclitaxel leads to robust synergistic reduction of tumor size in a preclinical model

2009 Cancer Research
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Abstract #1787: Characterization of the biochemical and cellular activity of the second-generation FLT3 inhibitor AC220

2009 Cancer Research
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Preface: special issue on medicinal chemistry of purines.

2009 Purinergic Signalling
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