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L. Belloni

Sapienza University of Rome

34

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2062

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THU-371-Modulation of H3K27 methylation by EZH2 and UTX/JMJD3 small molecules inhibitors impacts on proliferation and differentiation of hepatic progenitor cells and differentiated hepatocytes plasticity

2019 Journal of Hepatology
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A hyper-glycosylation of HBV surface antigen characterizes immunosuppression-driven HBV reactivation and hinders HBsAg recognition in vitro

2018 Journal of Hepatology
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The novel HBx mutation F30V correlates with hepatocellular carcinoma in vivo, reduces hepatitis B virus replicative efficiency and enhances anti-apoptotic activity of HBx N terminus in vitro

2018 Clinical Microbiology and Infection
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TP63 and TP73 in cancer, an unresolved “family” puzzle of complexity, redundancy and hierarchy

2014 FEBS Letters
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Polycomb protein enhancer of Zeste Homolog 2 (EZH2) protects human hepatocellular carcinoma (HCC) cells from DNA damage response (DDR) associated apoptosis

2014 Digestive and Liver Disease
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Epigenetic changes associated with the induction of vesicular steatosis in an in vitro cellular model

2014 Digestive and Liver Disease
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Epigenetic drugs targeting cccDNA-bound chromatin modifying enzymes silence HBV transcription and inhibit viral replication

2014 Digestive and Liver Disease
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Molecular Mechanisms of HBV-Associated Hepatocarcinogenesis

2013 Seminars in Liver Disease
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T-18 The HBV capsid inhibitors HAPs affect core protein interaction with the minichromosome and target cccDNA function

2013 Digestive and Liver Disease
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OC-22 Suppression of HBV transcription and replication by small molecules that target the epigenetic control of nuclear cccDNA minichromosome

2013 Digestive and Liver Disease
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