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Timothy J. Opperman

Indiana University Bloomington

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Adjunctive therapy for multidrug-resistant bacterial infections: Type III secretion system and efflux inhibitors.

2021 Drug Discovery Today
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Ribosome rescue inhibitors clear Neisseria gonorrhoeae in vivo using a new mechanism

2020 bioRxiv
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Optimization of a small-molecule Lipid II binder

2019 Bioorganic & Medicinal Chemistry Letters
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Pleiotropic Anti-Infective Effects of Defensin-Derived Antimicrobial Compounds

2018 Avian Diseases
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Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives

2016 Proceedings of the National Academy of Sciences of the United States of America
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Convallatoxin-Induced Reduction of Methionine Import Effectively Inhibits Human Cytomegalovirus Infection and Replication

2016 Journal of Virology
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Towards Development of Small Molecule Lipid II Inhibitors as Novel Antibiotics

2016 PLOS ONE
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DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-Indole Antibiotics

2016 Antimicrobial Agents and Chemotherapy
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DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-Indole Antibiotics

2016
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Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.

2015 Bioorganic & Medicinal Chemistry
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Citations (49)