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Nicholas E. Geacintov

New York University

474

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Variable inhibition of unwinding rates of DNA catalyzed by the SARS-Cov-2 (COV19) helicase nsp13 by structurally distinct single DNA lesions.

2021 bioRxiv
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Excision of Oxidatively Generated Guanine Lesions by Competitive DNA Repair Pathways

2021 International Journal of Molecular Sciences
- Vladimir Shafirovich
- Nicholas E. Geacintov
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Recognition and Repair of Oxidatively Generated DNA Lesions in Plasmid DNA by a Facilitated Diffusion Mechanism.

2021 Biochemical Journal
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Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote DNA exposure for lesion sensing.

2021 DNA Repair
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The DNA Damage-Sensing NER Repair Factor XPC-RAD23B Does Not Recognize Bulky DNA Lesions with a Missing Nucleotide Opposite the Lesion.

2020 bioRxiv
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TENT4A poly(A) polymerase regulates translesion DNA synthesis and is mutated in endometrial cancer

2020 bioRxiv
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TENT4A non-canonical poly(A) polymerase regulates DNA-damage tolerance via multiple pathways which are mutated in endometrial cancer

2020 bioRxiv
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Remarkable Enhancement of Nucleotide Excision Repair of a Bulky Guanine Lesion in a Covalently Closed Circular DNA Plasmid Relative to the Same, but Linearized Plasmid

2020 Biochemistry
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The DNA damage-sensing NER repair factor XPC-RAD23B does not recognize bulky DNA lesions with a missing nucleotide opposite the lesion

2020 DNA Repair
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Inhibition of Excision of Oxidatively Generated Hydantoin DNA Lesions by NEIL1 by the Competitive Binding of the Nucleotide Excision Repair Factor XPC-RAD23B.

2020 Biochemistry
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