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Judy Pawling

Lunenfeld-Tanenbaum Research Institute

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Proximity‐Dependent Sensors Reveal New Mechanisms of mTORC1 Activation by Amino Acids

2021 The FASEB Journal
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TMOD-18. DIRECT IN VIVO CRISPR SCREEN IDENTIFIES COOPERATING TUMOR SUPPRESSORS THAT DRIVE PROGRESSION OF IDH1-MUTANT LOW-GRADE GLIOMA TO AGGRESSIVE GLIOBLASTOMA

2021 Neuro-oncology
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The GATOR-Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids.

2020 Science
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Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

2020
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Systematic mapping of genetic interactions for de novo fatty acid synthesis

2019 bioRxiv
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Increasing cell permeability of N-acetylglucosamine via 6-acetylation enhances capacity to suppress T-helper 1 (TH1)/TH17 responses and autoimmunity

2019 PLOS ONE
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Mgat5 modulates the effect of early life stress on adult behavior and physical health in mice.

2016 Behavioural Brain Research
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Abstract 1031: Fumarate hydratase deficiency redirects glucose metabolism of hypoxic cancer cells into the pentose phosphate pathway

2016 Cancer Research
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Abstract LB-302: PTP1B regulates the Moyamoya disease-associated E3 ligase, RNF213 and cellular dioxygenase activity to allow breast tumor survival in hypoxia

2015 Cancer Research
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Golgi N-glycan branching N-acetylglucosaminyltransferases I, V and VI promote nutrient uptake and metabolism.

2015 Glycobiology
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