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John Robert Porter
John Robert Porter
UCB
Molecule
Small molecule
Tumor necrosis factor alpha
Trimer
Chemistry
2
Papers
10
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0
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Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.
2021
Nature Communications
David McMillan
Carlos Martinez-Fleites
John Robert Porter
David A. Fox
Rachel Davis
Prashant Mori
Tom Ceska
Bruce Carrington
Alastair David Griffiths Lawson
Tim Bourne
James OConnell
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Citations (6)
A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF.
2021
Nature Communications
Lightwood Daniel John
Rebecca Munro
John Robert Porter
David McMillan
Bruce Carrington
Alison Turner
Anthony Scott-Tucker
Elizabeth S. Hickford
Antje Schmidt
David A. Fox
Alison Maloney
Tom Ceska
Tim Bourne
James OConnell
Alastair David Griffiths Lawson
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Citations (4)
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