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R. Nowak

Harvard University

64

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Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

2019 Chemistry: A European Journal
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Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK).

2018 Journal of Medicinal Chemistry
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Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance

2018 Cell
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Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome

2018 eLife
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Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates.

2017 Journal of Molecular Biology
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Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment 5-(2-fluorophenyl)-1,3-oxazole-4-carboxylic acid (N09989b) (ligand modelled based on PANDDA event map, SGC - Diamond I04-1 fragment screening)

2017
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Crystal structure of the catalytic domain of human JARID1B in complex with MC3095

2017
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Crystal structure of the catalytic domain of human JARID1B in complex with MC3948

2017
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Crystal structure of the catalytic domain of human JARID1B in complex with D-2-hydroxyglutarate

2017
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Crystal structure of the catalytic domain of human JARID1B in complex with oxaloacetate

2017
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