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Shishir Chourey

Florida Institute of Technology

16

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Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys

2019 British Journal of Pharmacology
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Metabolism and pharmacokinetics of a potent N-acylindole antagonist of the OXE receptor for the eosinophil chemoattractant 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) in rats and monkeys

2018 European Journal of Pharmaceutical Sciences
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Structure-activity relationship study of β-oxidation resistant indole-based 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxo-ETE) receptor antagonists

2017 Bioorganic & Medicinal Chemistry Letters
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Pharmacokinetics and Metabolism of Selective Oxoeicosanoid (OXE) Receptor Antagonists and Their Effects on 5-Oxo-6,8,11,14-eicosatetraenoic Acid (5-Oxo-ETE)-Induced Granulocyte Activation in Monkeys

2016 Journal of Medicinal Chemistry
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Biosynthesis and actions of 5-oxoeicosatetraenoic acid (5-oxo-ETE) on feline granulocytes

2015 Biochemical Pharmacology
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Stereoselective synthesis of two highly potent 5-oxo-ETE receptor antagonists

2015 Tetrahedron Letters
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Inhibition of 5-Oxo-6,8,11,14-eicosatetraenoic Acid-Induced Activation of Neutrophils and Eosinophils by Novel Indole OXE Receptor Antagonists

2014 Journal of Medicinal Chemistry
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Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists

2014 Bioorganic & Medicinal Chemistry Letters
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Role of metal ion in specific recognition of pyrophosphate ion under physiological conditions and hydrolysis of the phosphoester linkage by alkaline phosphatase.

2013 Inorganic Chemistry
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Citations (45)