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Ulrich Matzner

University of Bonn

30

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864

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Deletion of fatty acid amide hydrolase reduces lyso-sulfatide levels but exacerbates metachromatic leukodystrophy in mice.

2021 Journal of Biological Chemistry
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Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction

2020 Annals of clinical and translational neurology
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Evolutionary redesign of the lysosomal enzyme arylsulfatase A increases efficacy of enzyme replacement therapy for metachromatic leukodystrophy

2019 Human Molecular Genetics
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Anti-inflammatory Therapy With Simvastatin Improves Neuroinflammation and CNS Function in a Mouse Model of Metachromatic Leukodystrophy

2015 Molecular Therapy
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Enzyme replacement therapy of a novel humanized mouse model of globoid cell leukodystrophy.

2015 Experimental Neurology
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Efficacy of enzyme replacement therapy in an aggravated mouse model of metachromatic leukodystrophy declines with age

2012 Human Molecular Genetics
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Lysosomal di-N-acetylchitobiase-deficient mouse tissues accumulate Man2GlcNAc2 and Man3GlcNAc2.

2012 Biochimica et Biophysica Acta
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Transport of arylsulfatase a across the blood-brain barrier in vitro

2011 Journal of Biological Chemistry
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Intracerebroventricular enzyme infusion corrects central nervous system pathology and dysfunction in a mouse model of metachromatic leukodystrophy

2011 Human Molecular Genetics
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Saposin B-dependent Reconstitution of Arylsulfatase A Activity in Vitro and in Cell Culture Models of Metachromatic Leukodystrophy

2009 Journal of Biological Chemistry
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