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B Oppers-Walgreen

Radboud University Nijmegen Medical Centre

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IL-1-driven cartilage and bone destruction are dependent on Toll-like receptor (TLR) 4, but not TLR2.

2005 Arthritis Research & Therapy
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Neutralizing synovial RANKL by local OPG gene therapy in collagen-induced arthritis prevents cartilage erosion through induction of a non-destructive type 2 synovitis.

2004 Arthritis Research & Therapy
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IL-18 expression in synovial biopsies of patients with active rheumatoid arthritis is associated with enhanced levels of both IL-1 and TNFα

2002 Arthritis Research & Therapy
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IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis.

2001 Journal of Immunology
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