Results of Cs needle interstitial implants for carcinoma of the tongue.
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✓ A coaxial two-catheter system that facilitates accurate stereotaxic placement of radioactive sources for the interstitial irradiation of brain tumors is described.
Coaxial
Radioactive source
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Prostate carcinoma
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Radiofrequency ablation (RFA), a local ablative modality, is gaining acceptance for the treatment of liver malignancies. Despite a relatively low complication rate, tumor seeding resulting from RFA in hepatocellular carcinoma (HCC) treatment can occur. A 44-year-old woman was diagnosed with HCC. Spiral computed tomography (CT) revealed a 2.3 × 2.0-cm mass in the S5 segment, which was treated with RFA on May, 2005. Follow-up imaging, performed at 6-month intervals after RFA, showed complete tumor necrosis. In October 2009, CT revealed a heterogeneous mass, 5.7 cm in diameter, in the right ovary. Since the lesion was limited to the right ovary without evidence of spread, bilateral salpingo-oophorectomy was performed. Histopathology indicated that the metastatic spread from the HCC to the ovary was positive for hepatocyte-specific antigen on immunohistochemistry. The ovary is a rare site for HCC metastasis. Moreover, needle tract implantation of HCC in the ovary is very rare.
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Objective To evaluate the usefulness of multiple RF needle electrodes in the treatment of hepatic cancer.Methods Eleven patients,7 of whom had 15 hepatocellular carcinoma nodules and 4 of whom had 7 hepatic metastatic nodules,underwent treatment by RF interstitial thermal ablation with multiple expandable needle electrodes.Twenty two tumor nodules were treated in 18 RF interstitial thermal ablation sessions with 34 needle electrode insertions.Sonography was performed 7 days after the RF interstitial thermal ablation treatment to evaluate the necrosis of the treated tumor.Results The average of RF ablations on tumor nodules was 1.3,average insertions of needle electrodes were 2.3;a mean course was 17.6 min for each RF heat damage to the tumor,no troubles seen due to the therapy.After a seven day therapy the color ultrasonography showed there remained tumorous tissues (residual) in four nodules of two cases of metastatic liver cancer,to whom second RF ablation therapy was given.Conclusion RF interstitial thermal ablation of hepatic tumor by expandable needle electrodes is a safe and effective method.Local ablation of tumors not exceeding 4.0 cm in diameter can be achieved only in one time without complications.
Rf ablation
Thermal ablation
Hepatic tumor
Liver Cancer
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Several papers have already been reported on the clinical use of hyperthermia to treat oral cancer. However, many of them were dealing with the treatment of cervical lymph node metastasis. Few reports of hyperthermia to treat primary lesion of oral cavity were found becouse of difficulty in applying hyperthermia. We are introducing and reporting the results of interstitial hyperthermia of cancer of the tongue using Implant Heating System (IHS) combined with other treatments.Six cases of cancer of the tongue has been treated. All cases were pathologically diagnosed as squamous cell carcinoma. Among 3 inoperable cases, the first case was treated by IHS (10 times), irradiation (60 Gy) and chemotherapy (CDDP : 200mg, PEP : 80mg), second case was treated by IHS (5 times), irradiation (23 Gy) and chemotherapy (5-FU : 2500mg) and the third case was treated by IHS (10 times) and chemotherapy (PEP : 80 mg, 5-FU : 2500mg). The other 3 cases were treated by hyperthermo -chemotherapy as a pre-operative therapy. These cases were treated by IHS (7 times) and chemotherapy (CDDP : 200mg, PEP : 70 mg).An IHS consists of three parts : ferromagnetic implant needle with low Curie point (Tc), induction coil and generator of high frequency magnetic field. The generator has 2.5 kw of maximum power, yielding the high frequency of 240 kHz. Ferro-magnetic implant (Fe-Pt alloy) is 1.8 mm in diameter and 15, 20, 25 mm in length, of which Curie point is set at 68°C. Hyperthermia was made using this system at 43°C for 45 minutes once or twice a week.The response were evaluated by clinical and pathological findings. The clinical response were 3 CR and 3 PR. The pathological findings in 3 cases of pre-operative hyperthermo-chemotherapy showed complete response. All cases are free of recurrence until now. Our results may indicate that hyperthermia using IHS combined with chemotherapy or radiation therapy is effective in the treatment of the oral cancer. It is expecting that this combination therapy will be a new mode of treatment for oral cancer.
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Breast implant
Breast carcinoma
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