Spatial metabolomics, LC-MS and RNA-Seq reveal the effect of red and white muscle on rabbit meat flavor
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White meat
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In this article,the study status about the flavor of meat at home and abroad was described,including the meat flavor precursor,the reaction and volatile flavor compounds that produced meat flavor.And the chemical substances on bacon flavor and the factors that affect the bacon flavor were mainly discussed.
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The field of metabolomics for cancer diagnosis and characterization is relatively new, and especially the application of metabolomics for in-vivo cancer imaging is still in its infancy. Cancer metabolomics involves the study of global variations of metabolites, with which malignancy conditions can be evaluated by profiling the entire measurable metabolome, instead of focusing only on certain metabolites or isolated metabolic pathways. At present, the study of cancer metabolomics is mainly accomplished utilizing magnetic resonance spectroscopy (MRS) and mass spectrometry (MS). These studies aim to uncover disease-specific metabolomic profiles in order to better understand variations in the involved pathways of cancer metabolism, and to utilize these profiles to establish metabolomic criteria for cancer detection, characterization, and patient prognostication and monitoring. The ultimate goal for cancer metabolomics is its implementation in the clinic to improve clinical abilities for cancer diagnosis and characterization, and through the development of in-vivo metabolomic imaging these clinical goals can be achieved noninvasively.
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cancer;
metabolomics;
metabolomic imaging;
magnetic resonance spectroscopy;
mass spectrometry
Metabolome
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Diacetyl
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The brewing of Chinese Baijiu is a microbial community fermentation system, in which there is a close and complex relationship between microorganisms and flavor quality, but the specific deep-seated mechanism still needs to be explored and interpreted continuously so far. In this review, Maotai flavor Baijiu was briefly introduced, and the microorganisms mainly affected by flavor substances, the main components of flavor substances, the factors affecting flavor formation and the application ways of functional microorganisms in Maotai flavor Baijiu were summarized. It provides a deeper understanding for the research of others flavor Baijiu.
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Metabolomics, the analysis of the metabolite profile in body fluids or tissues, is being applied to the analysis of a number of different diseases as well as being used in following responses to therapy. While genomics involves the study of gene expression and proteomics the expression of proteins, metabolomics investigates the consequences of the activity of these genes and proteins. There is good reason to think that metabolomics will find particular utility in the investigation of inflammation, given the multi-layered responses to infection and damage that are seen. This may be particularly relevant to eye disease, which may have tissue specific and systemic components. Metabolomic analysis can inform us about ocular or other body fluids and can therefore provide new information on pathways and processes involved in these responses. In this review, we explore the metabolic consequences of disease, in particular ocular conditions, and why the data may be usefully and uniquely assessed using the multiplexed analysis inherent in the metabolomic approach.
Functional Genomics
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Rabbit (cipher)
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SUMMARY The role of enzymes as agents for the restoration of fresh food flavor in processed foods is embodied in the “flavorese” concept of Hewitt et al. (1956). The experimental validity of this concept has been tested by adding a vegetable enzyme fraction to food prepared from the same or phylogenetically related vegetable. The flavor of the enzyme‐treated processed food approached that of the fresh vegetable hut was not identical with it. In general, addition of enzyme tended to over‐emphasize certain notes of the natural flavor. Odor changes were more readily detected than changes in taste. Both the qualitative and quantitative aspects of the flavor changes were affected by the processing of the vegetables, by the method and source of enzyme preparation, and by the conditions under which the alterations in flavor occurred. These results are discussed in light of the enzymology underlying the flavor changes.
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Each cell contains many different metabolites and chemical molecules which are generated during cellular process. All the metabolites present in a cell at a particular time is called metabolome. The study of all the metabolites and their modification in a particular condition is called metabolomics. Metabolome is closely linked with genotype, physiology and environment. So,in a nutshell, metabolomics is the study of substrates and products of metabolism which are influenced by the genetic and environmental factors. In plants, metabolomics has now been frequently developed and studied in biotic and abiotic stress resistance. High throughput metabolomics includes time efficient and effective metabolite profiling techniques. These techniques are chromatography based and chromatography free methods. Chromatographic methods are NMR, GC-MS and LC-MS . Chromatographv free techniques include DI-MS,FI-MS,MALDI and Ambient MS . This paper will give an idea about how metabolomics work in elucidating plants phenotype, how sample is prepared for metabolite profiling, different techniques of metabolite profiling and various metabolomic databases.
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Metabolite profiling
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Metabolomics is a field of systems biology that draws on the scientific methods of other groups to qualitatively or quantitatively characterize small molecule metabolites in organisms, revealing their interconnections with the state of the organism at an overall relative macroscopic level. Diabetic kidney disease (DKD) is well known as a chronic metabolic disease, and metabolomics provides an excellent platform for its clinical study. A growing number of metabolomic analyses have revealed that individuals with DKD have metabolic disturbances of multiple substances in their bodies. With the continuous development and improvement of metabolomic analysis technology, the application of metabolomics in the clinical research of DKD is also expanding. This review discusses the recent progress of metabolomics in the early diagnosis, disease prognosis, and pathogenesis of DKD at the level of small molecule metabolites in vivo.
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