Simplified treatment of hepatitis C during the COVID-19 pandemic: retrospective analysis of the British Columbia Hepatitis C Network
0
Citation
26
Reference
10
Related Paper
Abstract:
Background: The COVID-19 pandemic changed the landscape of hepatitis C virus (HCV) treatment in Canada. In this study, we sought to describe the characteristics, management, and outcomes of patients treated during the pandemic. Methods: Retrospective analysis of the British Columbia HCV Network included HCV patients treated from March 17, 2018 to February 22, 2022. Patients who started treatment before and after March 17, 2020 were designated pre-pandemic and pandemic groups, respectively. Patients were followed until sustained virologic response 12 weeks post-treatment (SVR12). Results: A total of 851 patients underwent 854 treatments, with 481 (56%) pre-pandemic and 373 (44%) pandemic. Pandemic patients were younger (median age 57 versus 61 pre-pandemic; p <0.01) and 23% were on opioid agonist therapy (versus 11% pre-pandemic; p = 0.01). Fewer pandemic patients completed transient elastography (36% versus 56% pre-pandemic; p < 0.01). Pandemic patients utilized fewer in-person appointments and more telehealth appointments ( p < 0.01). Fewer pandemic patients completed treatment (85% versus 91% pre-pandemic; p = 0.23); the SVR12 rate was 97.8% in those completing treatment and lab work (versus 99.5% pre-pandemic; p < 0.01). Younger age, substance use, and opioid agonist therapy were associated with loss to follow-up during the pandemic. Conclusions: Patients treated for HCV in British Columbia during the pandemic utilized fewer resources and had more loss to follow-up but maintained high SVR12 rates. Transitioning from in-person to telehealth appointments proved effective in a real-world setting. Individualized strategies are required for special populations prone to loss to follow-up.Keywords:
Pandemic
Hepatitis C
2019-20 coronavirus outbreak
2019-20 coronavirus outbreak
Coronavirus Infections
Betacoronavirus
Coronavirus
Pandemic
Cite
Citations (7)
2019-20 coronavirus outbreak
Pandemic
Betacoronavirus
Coronavirus Infections
Cite
Citations (0)
2019-20 coronavirus outbreak
Betacoronavirus
Coronavirus Infections
Pandemic
Cite
Citations (4)
COVID‐19 是一种由冠状病毒 SARS‐CoV‐2 引起的传染病。首先在中国武汉报告了第一例病例，然后感染随后传播到世界其他地方。除了感染的主要症状（发热、咳嗽和呼吸困难）外，还报告了不同类型的皮肤表现（体征）。最常见的类型是脚趾呈红色/紫色，类似于冻疮——这是一种皮肤疾病，通常与暴露在寒冷的温度下有关。这些与 COVID‐19 相关的“肢端病变”主要见于青少年和青年人，临床上被描述为“假性冻疮”。
2019-20 coronavirus outbreak
Betacoronavirus
Pandemic
Coronavirus Infections
Sars virus
Cite
Citations (0)
В статье рассмотрены возможные причины резидуальных психоневрологических нарушений («Long COVID», «Long haulers COVID») вследствие перенесенной инфекции COVID-19, и их коррекция в процессе медико-психологического сопровождения
2019-20 coronavirus outbreak
Betacoronavirus
Cite
Citations (0)
2019-20 coronavirus outbreak
Betacoronavirus
Coronavirus Infections
Pandemic
Cite
Citations (0)
Pandemic
2019-20 coronavirus outbreak
Coronavirus
Betacoronavirus
Coronavirus Infections
Cite
Citations (22)
2019-20 coronavirus outbreak
Betacoronavirus
Cite
Citations (0)
2019-20 coronavirus outbreak
Betacoronavirus
Coronavirus Infections
Pandemic
Cite
Citations (28)
Using tools such as crowdsourcing, machine learning, and molecule simulations, an open-science campaign known as COVID Moonshot Consortium drove the formulation of novel potential antiviral treatments for COVID-19, according to results published in Science.
2019-20 coronavirus outbreak
Crowdsourcing
Betacoronavirus
Coronavirus Infections
Pandemic
Cite
Citations (0)