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    Corrigendum to ‘The power of “controllers”: Transposon-mediated duplicated genes evolve towards neofunctionalization’ [Journal of Genetics and Genomics (2023) 50, 462–472]
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    Keywords:
    Neofunctionalization
    DNA Transposable Elements
    Summary An article in this issue of Molecular Microbiology by Cultrone et al. describes how a non‐autonomous helitron element could arise from its autonomous parent transposon by deletion followed by readthrough into an adjacent gene and its promoter, thus providing a mechanism for distribution of a specifically regulated promoter sequence around the genome, where it would have the potential to evolve new functions.
    DNA Transposable Elements
    Insertion sequence
    Sequence (biology)
    We determined the genomic sequence at the site of insertion in 2,266 unselected P element insertion events.Estimating physical properties of the genomic DNA at these insertion sites-such as base composition, bendability, A-philicity, protein-induced deformability, and B-DNA twist-revealed that they differ significantly from average chromosomal DNA.By examining potential hydrogen bonding sites in the major groove, we identified a 14-bp palindromic pattern centered on the 8-bp target site duplication that is generated by P element insertion.Our results suggest that the P-element transposition mechanism has a two-fold dyad symmetry and recognizes a structural feature at insertion sites, rather than a specific sequence motif.
    DNA Transposable Elements
    P element
    Citations (25)
    Abstract Biochemical and genetical analysis of plant transposons has shown that these elements can induce unstable mutations and also that the transposon structure can be altered in different ways. Upon insertion, a transposon can give rise to a variety of chromosomal changes in the vicinity of the insertion site. The alterations range from the nucleotide level to large‐scale rearrangements.
    DNA Transposable Elements
    Citations (8)