Reconstitution Dynamics and Impact on Clinical Outcomes of Mucosal-Associated Invariant T-Cells in Pediatric Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation
Federic GalavernaSara FlaminiIlaria PiliCarmen De LucaEmilia BoccieriFrancesca BeniniFrancesco QuagliarellaMarco RosichiniMarialuigia CatanosoMarianna CoccettiShirley GenahRoberto CartaFrancesca Del BufaloValentina BertainaMarco BecilliDaria PagliaraMattia AlgeriPietro MerliFranco LocatelliEnrico Velardi
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Graft‐ vs ‐host disease (GVHD) is a serious complication of hematopoietic stem cell transplantation (HSCT). Indications for HSCT have greatly expanded, and more patients are undergoing HSCT today than ever before. In addition, the options for immunosuppressive therapy for both prevention and treatment of GVHD have also expanded. These changes have in turn altered the landscape of this disease. We have reviewed the current literature on this subject and presented an update on this disease with a particular emphasis on mucosal manifestations.
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