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    Supplementary Table S1 from FH Variant Pathogenicity Promotes Purine Salvage Pathway Dependence in Kidney Cancer
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    Abstract:
    <p>Supplementary Table S1: FH variants with population frequencies, interpretations of pathogenicity, catalytic efficiencies, and multimerization states</p>
    Keywords:
    Kidney cancer
    Table (database)
    Arabidopsis DNA hypomethylation mutation, ddm1 , results in a variety of developmental abnormalities by slowly inducing heritable lesions at unlinked loci. Here, late‐flowering traits observed at high frequencies in independently‐established ddm1 lines were genetically characterized. In all of the four late‐flowering lines examined the traits were dominant and mapped to the same chromosomal region, which is close or possibly identical to the FWA locus. The ddm1 ‐induced phenotypic onsets are apparently not random mutation events, but specific to a group of genes, suggesting the underlying epigenetic mechanism. The DNA methylation mutant provide useful system for identifying epigenetically‐regulated genes important for plant development.
    RNA-Directed DNA Methylation