Fig 1 Gene Tree File from Conservation of Breast Cancer Molecular Subtypes and Transcriptional Patterns of Tumor Progression Across Distinct Ethnic Populations
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Fig 1 Gene Tree File from Conservation of Breast Cancer Molecular Subtypes and Transcriptional Patterns of Tumor Progression Across Distinct Ethnic PopulationsKeywords:
Tree (set theory)
Mendelian inheritance
Phosphoglucomutase
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TaqI
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Journal Article Dinucleotide repeat polymorphisms at the D5S257 and D5S268 loci on chromosome 5p Get access L.E. Bernard, L.E. Bernard Department of Medical Genetics, 6174 University Boulevard, University of British ColumbiaVancouver, BCV6T1Z3, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar C.N. Kreklywich, C.N. Kreklywich Department of Medical Genetics, 6174 University Boulevard, University of British ColumbiaVancouver, BCV6T1Z3, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar S. Wood S. Wood Department of Medical Genetics, 6174 University Boulevard, University of British ColumbiaVancouver, BCV6T1Z3, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 19, Issue 20, 25 October 1991, Page 5794, https://doi.org/10.1093/nar/19.20.5794 Published: 25 October 1991
Dinucleotide Repeat
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Coding region
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Complex breast cancer network constructed from experimentally verified seventy genes, by coordinating standard seven human protein and genome databases, follows hierarchical scale free features. Centrality based method of identification of inferred genes is implemented to this network and has predicted forty nine breast cancer genes, and nineteen non-breast cancer genes. As predicting good candidate genes before experimental analysis will save time and effort both. Fourteen genes out of nineteen are found to involve in various types of cancer and diseases, and five genes are engaged in non-cancer diseases. Some of the inferred genes need proper experimental investigation to understand fundamental roles of these genes in regulating breast cancer network.
Identification
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Developmental Biology
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Heterologous
Human genetics
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Arabidopsis DNA hypomethylation mutation, ddm1 , results in a variety of developmental abnormalities by slowly inducing heritable lesions at unlinked loci. Here, late‐flowering traits observed at high frequencies in independently‐established ddm1 lines were genetically characterized. In all of the four late‐flowering lines examined the traits were dominant and mapped to the same chromosomal region, which is close or possibly identical to the FWA locus. The ddm1 ‐induced phenotypic onsets are apparently not random mutation events, but specific to a group of genes, suggesting the underlying epigenetic mechanism. The DNA methylation mutant provide useful system for identifying epigenetically‐regulated genes important for plant development.
RNA-Directed DNA Methylation
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Phytophthora infestans
Phytophthora sojae
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