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    Investigation of new biomarkers that can be used for the diagnosis of asymptomatic diabetic peripheral artery disease (PAD): Serum netrin-1 levels can be a potential biomarker for the diagnosis of PAD
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    The aim of the present study was to investigate if alterations in protein S levels occur in peripheral arterial disease. In a group of 33 patients with peripheral arterial disease and in a group of 10 healthy volunteers we have the quantitative determination of functional protein S. The observer values show non significant difference in protein S levels among vasculopathic patients and controls (only five out of 33 patients showed low protein S levels). These data seem to suggest that low protein S levels do not play an important role in the development of peripheral arterial disease.
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